Oral Argument Read Online Free PDF

 
    Mr. Chief Justice, and may it please the court:
    Thank you, it’s good to be here. A special hearing convened by you is very special. I’m happy to answer your questions.
    Well, yes, the subpoena. But I’m happy too.
    No, I did not represent them in those years. And now I’m only serving as their spokesperson while their legal standing is being clarified.
    No, I don’t know where they are. But if I did, that would be a matter of attorney-client privilege.
    Spokesperson confidentiality, yes. Like protecting my sources. That’s what I meant to say.
    I do know what contempt of court means, yes. I brought my toothbrush.
    No, I’m happy to answer any questions you have. Really.
    Okay, sure. I met them when they were finishing their postdocs at MIT. I should clarify that they had no affiliation with MIT at the time they did the work in question, as MIT has proved.
    Their project involved identifying and removing problem parts in the biobricks catalog. After MIT shifted the catalog to the iGem website—
    No, I don’t think repudiated is the right word for that. MIT might have been worried about legal repercussions, but I don’t know. I came in later.
    Anyway, after that change of host, the iGem Registry of Standard Biological Parts grew much larger, and the parties for whom I am speaking found that there were questionable parts in the catalog, for instance a luminous bacteria that emitted lased light which unfortunately burned retinas, or—
    Sorry. I’ll try to be brief. While going through the biobricks catalog, my former clients found a seldom-used plasmid backbone called DragonSpineXXL, much longer than typical plasmid backbones. The DragonSpine’s designers apparently had hoped to enable bigger assemblages, but they encountered in vitro problems, including one that they called spina bifida—
    It’s a metaphor. I’m not a biochemist, I’m doing the best I can here. But to get to the point at your level of patience and understanding, as you so aptly put it, our bodies obtain their energy when the food we eat gets oxidized, producing ATP inside our mitochondria. ATP is the energy source used by all our cells. In plants, on the other hand, light striking the chloroplasts in leaves powers the production of ATP. Despite the different processes, the ATP is the same—
    Yes, I too was surprised. But all life forms on Earth share 938 base pairs of DNA, so it makes sense that there are some family resemblances. So, it occurred to my almost clients that—
    They consisted of a microbiologist, a systems biologist, a synthetic biologist, and an MD specializing in biochemistry and nutritional disorders—
    Yes, no doubt a good joke about the four of them walking into a bar could be concocted. But instead of that they found biobricks in the catalog that could be combined to make a synthetic chloroplast. They felt it would be possible to attach this synthetic chloroplast to a DragonSpine, and still have room to attach another assemblage they concocted, one where fascia cells formed hollow fibroblasts—
    Sorry. Fascia are bands of connective tissue. The bands are stretchy, and they’re all over inside us. They kind of hold our bodies together. Like your feet, have you ever had plantar fasciitis? No? You’re lucky. I guess you sit down on the job more than I do. Anyway, fascia consist of wavy bands of collagen blobs called fibroblasts. So, my acquaintances loaded DragonSpines with fibroblasts containing chloroplasts—
    Yes, I know it’s confusing. You are not biologists, I know. It’s easy to remember that. What it comes down to is that my sometime clients, using nothing but synthetic parts found in the Registry of Standard Biological Parts, created photosynthesizing human cells.
    Wait, excuse me, what you say is not correct. They didn’t want to patent it. They knew that the registry was an open source collection.
    I don’t think