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at the University of Mississippi Medical Center in Jackson. It was there that he met a surgical nurse with stunning green eyes, strawberry-blond hair, and a reputation for refusing dates with physicians or medical students. After three months of patience and charm, Will persuaded Karen to meet him for lunch, far from the hospital. There he discovered that the cause of her dating policy was simple: she’d seen too many nurses put medical students through school only to be cast aside later, and others caught in messy triangles with married doctors and their wives. In spite of her policy, she dated Will for the next two years—first secretly, then openly—and after a yearlong engagement, they married. Will entered private practice with a Jackson OB/GYN group the day after his honeymoon, and their adult life together began like a storybook.
    But during the second year of his practice, he began experiencing pain in his hands, feet, and lower back. He tried to ignore it, but soon the pain was interfering with his work, and he went to see a friend in the rheumatology department. A week later he was diagnosed with psoriatic arthritis, a severe, often crippling disease. Continuing as an obstetrician was impossible, so he began to investigate less physically rigorous fields like dermatology and radiology. His old college roommate suggested anesthesiology—his own specialty—a three-year program if the university would credit Will’s OB experience and let him skip the internship year. It did, and in 1993, he began his anesthesiology residency at UMC in Jackson.
    The same month, Karen quit her nursing job and enrolled at nearby Millsaps College for twenty-two hours of basic sciences in the premed program. Karen had always felt she aimed too low with nursing—and Will agreed—but her decision stunned him. It meant they would have to put off having children for several more years, and it would also force them to take on more debt than Will felt comfortable with. But he wanted Karen to be happy. While he trained for his new speciality and learned to deal with the pain of his disease, she racked up four semesters of perfect grades and scored in the ninety-sixth percentile on the Medical College Admissions Test. Will was as proud as he was surprised, and Karen was luminous with happiness. It almost seemed as though Will’s disease had been a gift.
    Then, during Karen’s freshman year of medical school—the third year of Will’s residency—she got pregnant. She had never been able to take the pill, and the less certain methods of birth control had finally failed. Will was surprised but happy; Karen was devastated. She believed that keeping the baby would mean the death of her dream of being a doctor. Will was forced to concede that she was probably right. For three agonizing weeks, she considered an abortion. The fact that she was thirty-three finally convinced her to keep the baby. She managed to complete her freshman year of med school, but after Abby was born, there was no question of continuing. She withdrew from the university the day Will completed his residency, and while Will joined the private anesthesiology group led by his old roommate, Karen went home to prepare for motherhood.
    They made a commitment to go forward without regrets, but it didn’t work out that way. Will was phenomenally successful in his work, and Abby brightened their lives in ways he could never have imagined. But Karen’s premature exit from medical school haunted her. Over the next couple of years, her resentment began to permeate their marriage, from their dinner conversations to their sex life. Or more accurately, their lack of one. Will tried to discuss it with her, but his attempts only seemed to aggravate the situation. He responded by focusing on his work and on Abby, and whatever energy he had left he used to fight his slowly progressing arthritis.
    He treated himself, which conventional wisdom declared folly, but he had studied his